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Aristolochic acid B

CAS No. 475-80-9

Aristolochic acid B ( Aristolochic acid B;Q100503; LS-102940; IIBRN-0329754 )

Catalog No. M18592 CAS No. 475-80-9

Aristolochic acid B is one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo.

Purity : 98%

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    Aristolochic acid B
  • Note
    Research use only, not for human use.
  • Brief Description
    Aristolochic acid B is one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo.
  • Description
    Aristolochic acid B is one of the major components of the carcinogenic plant extract aristolochic acid, is known to be mutagenic and to form DNA adducts in vitro and in vivo, Aristolochic acid B shows more carcinogenic risk than aristolochic acid I, and this may be, at least partly, the result of its increased levels in kidney and plasma.
  • Synonyms
    Aristolochic acid B;Q100503; LS-102940; IIBRN-0329754
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DNA mutation
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    475-80-9
  • Formula Weight
    311.25
  • Molecular Formula
    C16H9NO6
  • Purity
    98%
  • Solubility
    ——
  • SMILES
    OC(=O)c1cc2OCOc2c2c3ccccc3cc([N+]([O-])=O)c12
  • Chemical Name
    6-nitrophenanthro[3,4-d][1,3]dioxole-5-carboxylic acid

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Tian M, et al. Production, characterization of a monoclonal antibody against aristolochic acid-II and development of its assay system.[J]. Am J Chin Med, 2008, 36(02):425-436.
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